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NIH-sponsored trials:


ARCADIA—AtRial Cardiopathy and Antithrombotic Drugs In prevention After cryptogenic stroke
- UCSF PI: Karl Meisel, MD
- ZSFGH PI: Wade Smith MD, PhD
- Study populations: Ischemic stroke (ESUS with atrial cardiopathy)
- Purpose: The primary objective is to test the hypothesis that apixiban is superior to aspirin for the prevention of recurrent stroke in subjects with ESUS and atrial cardiopathy.
- Enrolling at: UCSF; ZSFGH


BASE—Biomarkers for Acute Stroke Study
- PI: Debbie Madhok, MD
- Study Population: Ischemic Stroke
- Purpose: To determine the effectiveness of clinically developed blood tests to stratify ischemic stroke and transient ischemic attack patients by cause.
- Enrolment at: UCSF; ZSFGH
Stroke AF – Rate of Atrial fibrillation through 12 months in patients with recent ischemic stroke of presumed known origin.
- PI: Karl Meisel, MD
- Study Population: Ischemic stroke (suspected large or small vessel cervical or intracranial atherosclerosis)
- Purpose: The purpose of the Stroke AF study is to compare the incidence of atrial fibrillation (AF) through 12 months between continuous cardiac rhythm monitoring with the Reveal LINQ™ Insertable Cardiac Monitor (ICM) (continuous monitoring arm) and standard of care (SoC) medical treatment (control arm) in subjects with a recent ischemic stroke of presumed known origin.
- Enrolling at: UCSF

Department/Gift Funded:

EPISODE-- Measuring cardiac head impulse to detect acute large vessel ischemic stroke
- PI: Wade Smith, MD, PhD
- Study Population: All code strokes who have undergone stroke imaging
- Purpose: Obtain physiological measurements within 30 minutes of baseline stroke imaging in order to develop algorithms for Head Pulse as well as Ceribell portable EEG that differentiate between emergent LVO, ICH and stroke mimics
- Enrolling at: UCSF